The show is aired on Zee TV, and currently shows child versions of the characters. However, it will take a leap of time and will show the two actors in their roles starting Sunday, said a statement.
Gagan was earlier seen in shows like "Pratha" and "Navya", while Neha is known for "Punar Vivaah" and "Chand Chupa Badal Mein".
Both of them are excited about their association with this big-ticket show, produced by Sagar Arts.
Gagan has done his homework to essay the role, and said: "Playing Ram, unlike any other character I have played so far, requires a great deal of preparation, be it in terms of reading up on the finer nuances of the Ramcharitmanas or studying and imbibing everything that Ram stood for."
"As an actor, it will be my endeavour to get the body language, the demeanour, the tonal quality of my voice and the diction right," he added.
The show's leading lady, Neha is upbeat as she has childhood memories of her grandmother narrating the tales from the Ramayan.
"She would tell us sisters about how each of us should strive to emulate Sita when we grow up. While I don't know if I have been successful in emulating Sita's virtues in my personal life, landing this role is the closest I will ever get to living out my granny's dream for all of us," said Neha.
Actor Neil Bhatt, who shot to fame as Abhi in "12/24 Karol Bagh", will play the role of Lakshman.