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||**~~**Diya Of The Week #12**~~**|| Extended (Page 12)

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vish.naren

IF-Dazzler

vish.naren

Joined: 08 May 2012

Posts: 4352

Posted: 01 March 2013 at 8:36pm | IP Logged
thanks a lot for encouragement...!! i shall answer today evening or tomo..! busy here in Institute, its our open day!!

@Samir, thanks for revealing the VM!!! :D

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vish.naren

IF-Dazzler

vish.naren

Joined: 08 May 2012

Posts: 4352

Posted: 03 March 2013 at 12:44am | IP Logged
Originally posted by -SamiR-

Really enjoying all your answers Vishnu Sa! Clap  btw .. your dodging skills are awesome! Star LOL

I got a question:

I think you're in research field right? Tell us about your research. Like give us a little abstract. Smile
Also, why did you choose the research field you are in?

o and .. my next thread will be for a VM! Smile

Yeah Samir Ji, I'm quiet enjoying...!!Embarrassed thanks to forum members...!!Embarrassed

Yeah, I'm in research field, and I'm under a new faculty and I'm his 1st Grad student and we are establishing a new lab! So right now I'm ordering things for the lab, a lot of office work going on. Currently making list of chemicals, enzymes and rest for the lab and ordering them! I'll start work only by April only!

Now research! I would ask u to keep a little more geeky here!

I hope you all know a little about CELL. 

We have DNA, then it is copied into RNA (Messenger RNA, mRNA) (by protein machinery called RNA polymerase. and known as Transciption), and which is read and coded into proteins (by Ribosome, a large complex consisting both RNA(ribosoal RNA , rRNA) and proteins, and known as Translation.).

The conversions of DNA into RNA and the final product proteins (in general, some RNA stays as such like part of Ribosome, and many other machines in cell) is called Gene Expression.

A gene expression is controlled in many levels.

1, formation of RNA (transcription level).
2, formation of Proteins ( translational level).
3, final degradation of Proetins by Proteosome Complex.

Now the above each step is governed by a huge system which can affect Initiation, Elongation or Stability of each mRNA.

In fact the Viruses utilizes the intricate mechanisms in above regulations to fool our cell, and cell fight back using the way they evolve to fool our system. So a Pathogen and Host co-evolve each other.

Now there are intricate small RNA copied from DNA of final proceed length called microRNA (miRNA) which bind to end sequences of a messenger RNA (mRNA) and destabilize the mRNA (its mechanism varies in plants and animals, though they share many commonalities).

Now anything that is formed in a cell needs to be targeted to degradation after use, or needs to be diverted for other purposes. Many molecules in cell do dual or multitasking and thus conserving energy.

We would be working in finding molecules and mechanisms involved in the micro RNA degradation. and How they are diverted in to doing other purposes other than messenger RNA destabilization.

And our model system is a worm! called Ceanorhabditis elegans. or C. elegans. 


A GIF image from Wiki

Its ideal since small and can be grown in small petri plates. and it reproduces faster, and is a hermaphrodite (only 2 sexes, male which is minor <5%, and hermaphrodite).
And last but not the least its TRANPARENT!! and each cell has been counted its position been attributed. In fact how single cell give rise to each is recorded. 

You may further read it simply from Wiki if interested.Embarrassed

http://en.wikipedia.org/wiki/Caenorhabditis_elegans

http://en.wikipedia.org/wiki/MicroRNA                              

(my research is under the title miRNA Turn Over!)

I know the above been a lecture, but believe me its more complicated!!!Tongue LOL

and I'm glad to know about ur next thread...!!EmbarrassedEmbarrassed

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vish.naren

IF-Dazzler

vish.naren

Joined: 08 May 2012

Posts: 4352

Posted: 03 March 2013 at 12:56am | IP Logged
Originally posted by Superman.

Shakalaka boom boom! Lets see how much you know about me, just for fun.. Cool

My height?
One inch less than mineEmbarrassed

My hair color?
Eyes color?
The one which u see in the mirror!Big smile

Favorite sport?
The one which u try hard, i think its football!Smile

Do I skate most, or cycle?
Skate, 've heard that there its diffi to cycle!Smile

My weakness?
U'r very much open!Embarrassed

My strength?
U'd stand to the word!Embarrassed

Who do I love the most in this forum?
I know its Sindu, though you'd say no!!EmbarrassedApprove

What's my favorite cartoon character?
Superman! (it started around like that na...Smile)

What's my age?
Age doesn't matter,  i shall consider you younger to me!Embarrassed

Guess my in real life nickname!Approve
sorry not good at that!Confused

Who am I closest to, dad ya mom?
DAD!Embarrassed

My favorite color?
Green!

More questions Embarrassed
Shocked

Am I annoying?
Nah! just don't consider so!Wink

Describe me in 5 words.
Skate, Sketch, Paint, DABH fan, Enthusiast...!!Smile

What do you like the most about me?
Your sketches!!Embarrassed, n recent reply in DOTW thread!!Embarrassed

What do you dislike about me?
nothing much except occasional spamming, and at times enjoy them also!Big smile

How would you react if I left the forum forever, dododo?
Oh no, not another memb!Shocked (However I hope I would remain active to witness all those!Confused)

If you could marry any actress in this while world, who would you choose?
None!Star they would only ACT na...!!Wink

DaaamN, good luck

I hope I pass the test Ma'am!Embarrassed

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vish.naren

IF-Dazzler

vish.naren

Joined: 08 May 2012

Posts: 4352

Posted: 03 March 2013 at 12:57am | IP Logged
thanks to Bharathi Akka, for extending the thread,Hug

now you may choose another one, or continue to spam here...!!Big smile

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farhana874

Fizak

Goldie

Fizak

Joined: 29 January 2005

Posts: 2297

Posted: 03 March 2013 at 7:33am | IP Logged
I m late to congratulate you Embarrassed.. but it seems after ages ur wish for being DOTW was fulfilled LOL and u seems to enjoy & answers them awesomely Thumbs Up
 
Liked to ur inputs about ur research work Clap

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farhana874vish.naren

-SamiR-

Goldie

-SamiR-

Joined: 12 October 2012

Posts: 1406

Posted: 03 March 2013 at 7:54am | IP Logged
Vishnu Sa - oh wow! So you're practically setting up a new lab! No wonder you're so busy! 
Thanks for the detailed reply. Your topic of research is very interesting; especially the second part .. about the different roles and purposes of miRNA! Wish you all the best Vishnu! I'm sure you will publish many papers in the future! Smile If I ever need more info on miRNAs .. I'll know who to ask! Big smile

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farhana874vish.naren

vish.naren

IF-Dazzler

vish.naren

Joined: 08 May 2012

Posts: 4352

Posted: 03 March 2013 at 8:45pm | IP Logged
Originally posted by Fizak

I m late to congratulate you Embarrassed.. but it seems after ages ur wish for being DOTW was fulfilled LOL and u seems to enjoy & answers them awesomely Thumbs Up
 
Liked to ur inputs about ur research work Clap

Thanks Fiza...!!SmileSmile na its not late at all..!! Embarrassed 

Yeah the dream is fulfilled with me on one the serving table...!!LOLTongue

some how i'm managing to dodge! or in other words they are yet to grill me to the real sense!!Wink

Glad you like them!! that the best I can try explaining!!Smile

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farhana874

vish.naren

IF-Dazzler

vish.naren

Joined: 08 May 2012

Posts: 4352

Posted: 03 March 2013 at 8:47pm | IP Logged
Originally posted by -SamiR-

Vishnu Sa - oh wow! So you're practically setting up a new lab! No wonder you're so busy! 
Thanks for the detailed reply. Your topic of research is very interesting; especially the second part .. about the different roles and purposes of miRNA! Wish you all the best Vishnu! I'm sure you will publish many papers in the future! Smile If I ever need more info on miRNAs .. I'll know who to ask! Big smile

Yeah, I'm setting up a new lab, so lots of list to make, enquiries, collecting and proceeding quotations, now office work!!! 

Glad you kinda like them! and thanks for your wishes!!!EmbarrassedEmbarrassed

Hopefully I would manage to publish nice ones!!Big smile

Sure u can ask any tame!! by the by whats your background?Smile

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-SamiR-farhana874

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