Sam: What you like him better or something?
Cas: Dean and I do share a more profound bond...I wasn't going to mention it.
Cas (while talking to Dean on cellphone): This isn't funny, Dean. The voice says I'm almost out of minutes.
Cas: This is a den of iniquity. I should not be here.
Dean: Cas, we've talked about this. Personal space?
Cas: My apologies.
Sam: What happened to him? (Pointing at the beaten-up Dean)
Dean: So what, you're like a DeLorean without enough plutonium?
Cas: I don't understand that reference (like any others).
Sam: Are you okay?
Cas: Don't ask stupid questions.
(Love the way he says that in Sam's ear)
Raphael: I will find you!
Castiel: Maybe one day, but today you're my little b*tch.
Dean (on phone): Cas, it's Dean. Yeah, room 31 C, basement level, St. James Medical Center...
Cas (appears in front of him): I'm there now.
Dean: Yeah, I get that.
Cas: I'm gonna hang up now.
Sam: Take care of these guys, okay?
Cas: That's not possible.
Sam: Then humor me.
Cas: Oh. I was supposed to lie. (chuckles and continues with an expression that yells "I'm lying!!"
) Uh... sure. They'll be fine, I...
Sam: Just--just stop... talking.
Cas: I suggest we imbibe copious quantities of alcohol... just wait for the inevitable blast wave.
Dean: Yes, well, thank you, Bukowski.
Cas: Please, accept this sandwich as a gesture of solidarity.
Dean: What's the word, Cas?
Castiel: It's the shortened version of my name.
Cas: Sam, Dean, my "people skills" are "rusty." Pardon me, but I've spent the last "year" as a multidimensional wavelength of celestial intent.
Cas: You only have 24 hours.
Sam: What? Why?
Cas: Well, the answer to your question can best be expressed as a series of partial differential equations...
Bobby: Aim lower.
Cas: [about the hamburger he's eating] These make me very happy.
Dean: Seriously, how many is that?
Cas: I lost count, but it's in the low hundreds.