Sai was born in Pune to a Marathi father and Bengali mother. Sai got married to her on-screen co-star, Shakti Anand of Saara Aakaash. Sai has virtually grown up in the film industry and has been facing the camera since she was three. Acting has been an aspiration ever since. But, whether TV or films, Sai did only meaningful roles. Sai doesn't want to associate with skimpy outfits and sexy scenes.
Sai went to Mumbai to make her career in modeling and eventually got the role in 'Saara Aakaash'. Sai also played the female lead in Ek Ladki Anjaani Si. Recently, she has appeared in Kashi on Imagine TV, where she played the role of a mother of 6 years old girl. Sai is also busy in shooting of an unnamed film to be produced by her husband Shakti Anand.